Dr. Baer and colleagues’ paper, “Bias and evolution of the mutationally accessible phenotypic space in a developmental system” published in PLoS Genetics 2010 6(3), was named by the Faculty of 1000 Biology as one most important advances in biology. Dr. Rainey’s (reviewer) comments: “This paper adds to the growing body of experimental evidence which shows that genetic/developmental constraints bias the variation presented to selection and thus affect the course of phenotypic evolution.” Congrats!