Alice Harmon


Ph.D., University of Georgia, 1985

harmon621 Carr Hall
(352) 392-9169

Research Interests

Plants respond to a variety of stimuli including light, growth regulators, touch, environmental stress, and pathogen attack. Many of the responses are brought about by an increase in intracellular free calcium concentration. My lab focuses on the molecular events that occur as a result of this change in calcium concentration. Specifically, we are studying a family of protein kinases whose activities are stimulated by calcium, and which are responsible for eliciting physiological changes. These protein kinases are called calcium-dependent protein kinases or CDPKs.

Representative Publications

  • Harper, J.F., Bretton, G. and A.C. Harmon, 2004, Decoding Ca 2+ signals through plant protein kinases, Annu. Rev. Plant Biol. 55:263-288
  • Harper, J.F. and A.C. Harmon, 2005, Plants, Symbiosis, and Parasites: A Calcium Signaling Connection, Nature Rev. Mol. Cell Biol. 6:555-566
  • Stevens, S.M., Jr., A.Y. Chung, M.C. Chow, S.H. McClung, C.N. Strachan, A.C. Harmon, N.D. Denslow, and L Prokai, 2005, Enhancement of phosphoprotein analysis using a florescent affinity tag and mass spectrometry. Rapid Commun. Mass Spec. 19:2157-2162
  • Hegeman, A.D. M. Rodriguez, B.W. Han, Y. Uno, G.N. Phillips Jr., E.M. Hrabak, J.C. Cushman, J.F. Harper, A.C. Harmon, M.R. Sussman A phyloproteomic characterization of in vitro autophosphorylation in calcium-dependent protein kinases, Proteomics, 6:3649-3664
  • Chen, S. and A.C. Harmon, 2006, Advances in Plant Proteomics, Proteomics
  • Liu, F., B.-C. Yoo, J.-Y. Lee, W. Pan, and A.C. Harmon 2006 Calcium-regulated phosphorylation of soybean serine acetyltransferase in response to oxidative stress, J. Biol. Chem. 281:27405-27415